BDBM50214995 CHEMBL245678::N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE::cis-N-(2-(5-chloro-1H-indole-2-carboxamido)cyclohexyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide

SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key InChIKey=ARPFWVKYXJZULB-DLBZAZTESA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50214995   

TargetProthrombin(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human factor 2a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetProthrombin(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human factor 2a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCoagulation factor X(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCoagulation factor X(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCoagulation factor X(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCoagulation factor X(Human)
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50214995(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human factor 10a after 10 secondsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)