BDBM50215172 1-(2,6-difluoro-benzyl)-7-[pyridin-4-yl-methyl]-3-(3-methoxy-phenyl)-5,6,7,8-tetrahydro-1H-pyrido[3,4-d]pyrimidine-2,4-dione::CHEMBL236750

SMILES COc1cccc(c1)-n1c(=O)c2CCN(Cc3ccncc3)Cc2n(Cc2c(F)cccc2F)c1=O

InChI Key InChIKey=CMQULUBHHJNGBL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215172   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50215172(1-(2,6-difluoro-benzyl)-7-[pyridin-4-yl-methyl]-3-...)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [125I]His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed