BDBM50215220 1-(2,6-difluoro-benzyl)-7-[2-(1H-indol-3-yl)-ethyl]-3-(3-methoxy-phenyl)-5,6,7,8-tetrahydro-1H-pyrido[3,4-d]pyrimidine-2,4-dione::CHEMBL412581

SMILES COc1cccc(c1)-n1c(=O)c2CCN(CCc3c[nH]c4ccccc34)Cc2n(Cc2c(F)cccc2F)c1=O

InChI Key InChIKey=SIJLLGCJSPPEJZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215220   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50215220(1-(2,6-difluoro-benzyl)-7-[2-(1H-indol-3-yl)-ethyl...)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [125I-His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed