BDBM50215659 1-(4-(2-(aminomethyl)thiazol-5-yl)cyclohex-3-enyl)-3-(3-chloro-4-fluorophenyl)-1-(2-(pyrrolidin-1-yl)ethyl)urea::CHEMBL388524

SMILES NCc1ncc(s1)C1=CCC(CC1)N(CCN1CCCC1)C(=O)Nc1ccc(F)c(Cl)c1

InChI Key InChIKey=SJSUVBILNKORMJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215659   

TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50215659(1-(4-(2-(aminomethyl)thiazol-5-yl)cyclohex-3-enyl)...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50215659(1-(4-(2-(aminomethyl)thiazol-5-yl)cyclohex-3-enyl)...)
Affinity DataKi:  13nMAssay Description:Antagonist activity at MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50215659(1-(4-(2-(aminomethyl)thiazol-5-yl)cyclohex-3-enyl)...)
Affinity DataKi:  13nMAssay Description:Antagonist activity at MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed