BDBM50215757 3-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-pyrazol-4-yl)vinyl)pyridine::CHEMBL246165

SMILES FC(F)(F)c1cnc([nH]1)-c1n[nH]cc1C=Cc1cccnc1

InChI Key InChIKey=OKRLCDNMDXJZIY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215757   

TargetAurora kinase A(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215757(3-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215757(3-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215757(3-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed