BDBM50215991 4-(quinolin-4-ylmethoxy)-N-(3-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)propyl)benzamide::CHEMBL248523

SMILES O=C(NCCCc1n[nH]c(=S)[nH]1)c1ccc(OCc2ccnc3ccccc23)cc1

InChI Key InChIKey=AZDMTLYFRFXZGD-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50215991   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215991(4-(quinolin-4-ylmethoxy)-N-(3-(5-thioxo-4,5-dihydr...)
Affinity DataIC50: 294nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215991(4-(quinolin-4-ylmethoxy)-N-(3-(5-thioxo-4,5-dihydr...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215991(4-(quinolin-4-ylmethoxy)-N-(3-(5-thioxo-4,5-dihydr...)
Affinity DataKi: >4.50E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215991(4-(quinolin-4-ylmethoxy)-N-(3-(5-thioxo-4,5-dihydr...)
Affinity DataKi: >5.03E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215991(4-(quinolin-4-ylmethoxy)-N-(3-(5-thioxo-4,5-dihydr...)
Affinity DataKi: >6.02E+3nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215991(4-(quinolin-4-ylmethoxy)-N-(3-(5-thioxo-4,5-dihydr...)
Affinity DataKi: >6.37E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed