BDBM50216407 CHEMBL395075::isoquinolinesulfon-5-yl-[2-oxo-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]amide

SMILES O=C(CNS(=O)(=O)c1cccc2cnccc12)N1CCN(CC1)c1ncccn1

InChI Key InChIKey=VVRLXSOOICFMLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216407   

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216407(CHEMBL395075 | isoquinolinesulfon-5-yl-[2-oxo-2-(4...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed