BDBM50216488 5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione::CHEMBL398171

SMILES Clc1ccccc1Cc1c([nH]c(=O)[nH]c1=O)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=ZBJXBIMZENDRKV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216488   

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216488(5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216488(5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  50nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMineralocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216488(5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  3.49E+3nMAssay Description:Displacement of [3H]aldosterone from mineralocorticoid receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed