BDBM50216557 5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benzamido)cyclopentyl)thiophene-2-carboxamide::CHEMBL399593

SMILES Clc1ccc(s1)C(=O)N[C@@H]1CCC[C@@H]1NC(=O)c1ccc(cc1)N1CCCCC1=O

InChI Key InChIKey=FIUKRBJFYYATCX-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50216557   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216557(5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216557(5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...)
Affinity DataKi:  8.87E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216557(5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216557(5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216557(5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216557(5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...)
Affinity DataKi: >1.40E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216557(5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216557(5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...)
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed