BDBM50216675 CHEMBL247648::tert-butyl (R)-3-(2-fluoro-6-(trifluoromethyl)phenyl)-1-((R)-1-isopropyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-ylamino)-1-oxopropan-2-ylcarbamate

SMILES CC(C)N1c2ccccc2CC[C@@H](NC(=O)[C@@H](Cc2c(F)cccc2C(F)(F)F)NC(=O)OC(C)(C)C)C1=O

InChI Key InChIKey=GCNBHLMIBIUQQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216675   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216675(tert-butyl (R)-3-(2-fluoro-6-(trifluoromethyl)phen...)
Affinity DataIC50: 32nMAssay Description:Blockade of human Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed