BDBM50216686 3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinolin-8-yl)acrylamide::CHEMBL225971

SMILES Clc1ccccc1-c1ccc(\C=C(/C#N)C(=O)Nc2cccc3cccnc23)o1

InChI Key InChIKey=XPCOAVYCHRMBET-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216686   

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216686(3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant SIRT3 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216686(3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant SIRT1 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216686(3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant SIRT2 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed