BDBM50217198 CHEMBL391779::N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((4-(methylamino)piperidin-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

SMILES CNC1CCN(Cc2ccn3ncnc(Nc4ccc5n(Cc6cccc(F)c6)ncc5c4)c23)CC1

InChI Key InChIKey=MLYHNVDOBUQIID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217198   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50217198(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((4-(meth...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant HER2 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50217198(N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((4-(meth...)
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant EGFR expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed