BDBM50217435 2S,4R,20S-4-{[2-carboxy-2-(2,4,6-trimethyl-benzenesulfonylamino)-ethylcarbamoyl]-methoxy}-2-[(4-methoxy-pyridin-2-ylamino)-methyl]-pyrrolidine-1-carboxylic acid benzyl ester::CHEMBL398192

SMILES COc1ccnc(NC[C@@H]2C[C@H](CN2C(=O)OCc2ccccc2)OCC(=O)NC[C@H](NS(=O)(=O)c2c(C)cc(C)cc2C)C(O)=O)c1

InChI Key InChIKey=CGSLGBRMSMBNMX-ITHJLQSDSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50217435   

TargetIntegrin alpha-V/beta-5(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50217435(2S,4R,20S-4-{[2-carboxy-2-(2,4,6-trimethyl-benzene...)
Affinity DataIC50:  19nMAssay Description:Inhibition of integrin alphaVbeta5 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-V/beta-3(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50217435(2S,4R,20S-4-{[2-carboxy-2-(2,4,6-trimethyl-benzene...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of integrin alphaVbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-IIb/beta-3(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50217435(2S,4R,20S-4-{[2-carboxy-2-(2,4,6-trimethyl-benzene...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of integrin alpha2bbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-5/beta-1(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50217435(2S,4R,20S-4-{[2-carboxy-2-(2,4,6-trimethyl-benzene...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of integrin alpha5beta1 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed