BDBM50217570 CHEMBL236675::N-methyl(5-(4-morpholinobut-1-ynyl)-2-(4-(trifluoromethyl)phenoxy)phenyl)methanamine

SMILES CNCc1cc(ccc1Oc1ccc(cc1)C(F)(F)F)C#CCCN1CCOCC1

InChI Key InChIKey=RVSCXYLNWULPGJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217570   

TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217570(N-methyl(5-(4-morpholinobut-1-ynyl)-2-(4-(trifluor...)
Affinity DataKi:  2nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217570(N-methyl(5-(4-morpholinobut-1-ynyl)-2-(4-(trifluor...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217570(N-methyl(5-(4-morpholinobut-1-ynyl)-2-(4-(trifluor...)
Affinity DataKi:  7.30nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed