BDBM50217578 CHEMBL391947::N-methyl(2-(3-methyl-4-(methylthio)phenoxy)-5-(4-morpholinobut-1-ynyl)phenyl)methanamine

SMILES CNCc1cc(ccc1Oc1ccc(SC)c(C)c1)C#CCCN1CCOCC1

InChI Key InChIKey=KUYNMYBNRQCGCC-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50217578   

TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217578(N-methyl(2-(3-methyl-4-(methylthio)phenoxy)-5-(4-m...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217578(N-methyl(2-(3-methyl-4-(methylthio)phenoxy)-5-(4-m...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217578(N-methyl(2-(3-methyl-4-(methylthio)phenoxy)-5-(4-m...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217578(N-methyl(2-(3-methyl-4-(methylthio)phenoxy)-5-(4-m...)
Affinity DataKi:  240nMAssay Description:Binding affinity to human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217578(N-methyl(2-(3-methyl-4-(methylthio)phenoxy)-5-(4-m...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed