BDBM50217588 (2-(3,4-dichlorophenoxy)-5-(4-(4-fluoropiperidin-1-yl)but-1-ynyl)phenyl)-N-methylmethanamine::CHEMBL237747

SMILES CNCc1cc(ccc1Oc1ccc(Cl)c(Cl)c1)C#CCCN1CCC(F)CC1

InChI Key InChIKey=QSADIYOOZUGQQY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217588   

TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217588((2-(3,4-dichlorophenoxy)-5-(4-(4-fluoropiperidin-1...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217588((2-(3,4-dichlorophenoxy)-5-(4-(4-fluoropiperidin-1...)
Affinity DataKi:  14nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217588((2-(3,4-dichlorophenoxy)-5-(4-(4-fluoropiperidin-1...)
Affinity DataKi:  27nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed