BDBM50217885 3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-piperidin-3-yl-1H-pyrrolo[2,3-b]pyridine::CHEMBL236772

SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12

InChI Key InChIKey=DJHAAKDZLZSXFT-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217885   

Target5-hydroxytryptamine receptor 6(Human)
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217885(3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-piperidi...)
Affinity DataKi:  4.57nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217885(3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-piperidi...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217885(3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-piperidi...)
Affinity DataEC50:  273nMAssay Description:Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed