BDBM50217887 3-[(2-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpyrrolo[2,3-b]pyridine::CHEMBL393830

SMILES Clc1ccccc1S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12

InChI Key InChIKey=TXYHQHSGNGSQQE-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217887   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217887(3-[(2-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217887(3-[(2-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...)
Affinity DataKi:  3.72nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217887(3-[(2-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed