BDBM50217903 3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-(1-methylpiperidin-3-yl)-1H-pyrrolo[2,3-b]pyridine::CHEMBL401018

SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=LTLJCRZLNGLYAB-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217903   

Target5-hydroxytryptamine receptor 6(Human)
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217903(3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-(1-methy...)
Affinity DataKi:  2.09nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217903(3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-(1-methy...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217903(3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-(1-methy...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed