BDBM50218228 3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(phenyl)pyrrolidin-1-yl)-6,6-dimethylcyclohex-2-enone::CHEMBL400393

SMILES C[C@@H](O[C@@H]1CN(C[C@H]1c1ccccc1)C1=CC(=O)C(C)(C)CC1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=SONMMNBUJANHDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218228   

TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50218228(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.180nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed