BDBM50218434 4-[5,7,7,10,10-pentamethyl-2-(4-trifluoromethoxy-phenylsulfanyl)-7,8,9,10-tetrahydro-5H-5,13-diaza-benzo[4,5]cyclohepta[1,2-b]naphthalen-12-yl]-benzoic acid::CHEMBL395564

SMILES CN1c2ccc(Sc3ccc(OC(F)(F)F)cc3)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C

InChI Key InChIKey=RFSIKHPICUTFEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218434   

TargetRetinoic acid receptor RXR-alpha(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50218434(4-[5,7,7,10,10-pentamethyl-2-(4-trifluoromethoxy-p...)
Affinity DataIC50: 390nMAssay Description:Inhibition of 9-cis-retinoic acid-induced RXRalpha transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50218434(4-[5,7,7,10,10-pentamethyl-2-(4-trifluoromethoxy-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LG-100268-induced RXRalpha transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed