BDBM50219273 (Z)-(5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)quinolin-5-yl)oxazol-4-yl)(4-((methoxyimino)(pyridin-2-yl)methyl)piperidin-1-yl)methanone::CHEMBL400976

SMILES CO\N=C(\C1CCN(CC1)C(=O)c1nc(oc1CN)-c1ccc(OC)c2nc(ccc12)C(F)(F)F)c1ccccn1

InChI Key InChIKey=LKJQBYPVUKVMQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219273   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219273((Z)-(5-(aminomethyl)-2-(8-methoxy-2-(trifluorometh...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219273((Z)-(5-(aminomethyl)-2-(8-methoxy-2-(trifluorometh...)
Affinity DataIC50: 120nMAssay Description:Inhibition of PDE10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219273((Z)-(5-(aminomethyl)-2-(8-methoxy-2-(trifluorometh...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE11More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed