BDBM50219539 (R)-3-ethyl-4-(2,2,2-trifluoroethyl)-10-(trifluoromethyl)-3,4-dihydro-2H-[1,4]oxazino[2,3-f]quinolin-8(7H)-one::CHEMBL250897

SMILES CC[C@@H]1COc2c(ccc3[nH]c(=O)cc(c23)C(F)(F)F)N1CC(F)(F)F

InChI Key InChIKey=FGMYUHULLBIYFO-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50219539   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219539((R)-3-ethyl-4-(2,2,2-trifluoroethyl)-10-(trifluoro...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219539((R)-3-ethyl-4-(2,2,2-trifluoroethyl)-10-(trifluoro...)
Affinity DataIC50: 520nMAssay Description:Antagonist activity at progesterone receptor by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219539((R)-3-ethyl-4-(2,2,2-trifluoroethyl)-10-(trifluoro...)
Affinity DataIC50: 1.51E+3nMAssay Description:Antagonist activity at glucocorticoid receptor by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219539((R)-3-ethyl-4-(2,2,2-trifluoroethyl)-10-(trifluoro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed