BDBM50220586 1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-ethyl]-4-phenyl-piperidin-4-ol::6-(2-(4-(3-fluorophenyl)-4-hydroxypiperidin-1-yl)-1-hydroxyethyl)-3,4-dihydroquinolin-2(1H)-one::CHEMBL246819

SMILES OC(CN1CCC(O)(CC1)c1cccc(F)c1)c1ccc2NC(=O)CCc2c1

InChI Key InChIKey=ZTOSZJPNPROTBL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50220586   

LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 9.80E+3nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50220586(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of [3H]bufuralol from hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed