BDBM50220693 (R)-N-((S)-3-(4-chlorophenyl)-1-(4-(cyanomethyl)-4-cyclohexylpiperidin-1-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL251735

SMILES Clc1ccc(C[C@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC(CC#N)(CC2)C2CCCCC2)cc1

InChI Key InChIKey=HWPJSWOYUFQNLK-WDYNHAJCSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220693   

TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220693((R)-N-((S)-3-(4-chlorophenyl)-1-(4-(cyanomethyl)-4...)
Affinity DataEC50:  189nMAssay Description:Antagonist activity at human MC4R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220693((R)-N-((S)-3-(4-chlorophenyl)-1-(4-(cyanomethyl)-4...)
Affinity DataIC50:  6.80nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220693((R)-N-((S)-3-(4-chlorophenyl)-1-(4-(cyanomethyl)-4...)
Affinity DataEC50:  640nMAssay Description:Antagonist activity at human MC5R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed