BDBM50221116 1-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-((S)-1-(2-hydroxyethylamino)-3-methylbutyl)-4-(trifluoromethyl)phenyl)piperazin-1-yl)-1-oxopropan-2-yl)pyrrolidin-2-one::CHEMBL396884

SMILES CC(C)C[C@H](NCCO)c1cc(ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O)C(F)(F)F

InChI Key InChIKey=YNRLVFCAEWMMDT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221116   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50221116(1-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-((S)-1-(2-hy...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity at human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50221116(1-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-((S)-1-(2-hy...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of microsomal CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed