BDBM50221217 1-(1-(3-(4-(5-chloro-1H-indol-3-yl)piperidin-1-yl)-2-hydroxypropyl)-3-(4-(trifluoromethyl)phenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)ethanone::CHEMBL397152

SMILES CC(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)cc3)nn2CC(O)CN2CCC(c3c[nH]c4ccc(Cl)cc34)CC2)C1

InChI Key InChIKey=HZRPYRWADRQXAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221217   

TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221217BDBM50221217(1-(1-(3-(4-(5-chloro-1H-indol-3-yl)piperidin-1-yl)...)
Affinity DataIC50: 95nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed