BDBM50221413 (1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol::CHEMBL248839

SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2c2[nH]c4ccc(F)cc4c2C[C@@]3(O)[C@H]1C5

InChI Key InChIKey=TUMHJCRNWJSMQK-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50221413   

TargetDelta-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221413BDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]p-Cl-DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221413BDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataEC50:  16nMAssay Description:Activity at delta opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221413BDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataKi:  21nMAssay Description:Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221413BDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221413BDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataEC50:  1.08E+3nMAssay Description:Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed