BDBM50221422 (S)-2-amino-N-(3-(5,6-dimethyl-3-oxo-3,4-dihydropyrazin-2-yl)propyl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL437372

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCc1nc(C)c(C)[nH]c1=O

InChI Key InChIKey=HWDRXUZQHRTTNY-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221422   

TargetMu-type opioid receptor(Human)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50221422((S)-2-amino-N-(3-(5,6-dimethyl-3-oxo-3,4-dihydropy...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50221422((S)-2-amino-N-(3-(5,6-dimethyl-3-oxo-3,4-dihydropy...)
Affinity DataKi:  269nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50221422((S)-2-amino-N-(3-(5,6-dimethyl-3-oxo-3,4-dihydropy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50221422((S)-2-amino-N-(3-(5,6-dimethyl-3-oxo-3,4-dihydropy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed