BDBM50221683 9-(4-hydroxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione::CHEMBL441145

SMILES Cn1c2nc3N(CCc4ccc(O)cc4)CCCn3c2c(=O)n(C)c1=O

InChI Key InChIKey=DDBFFDSEFYGLOU-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50221683   

TargetAdenosine receptor A2a(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50221683(9-(4-hydroxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50221683(9-(4-hydroxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)
Affinity DataEC50:  302nMAssay Description:Antagonist activity at human adenosine receptor A2a expressed in CHO cell membranes assessed as inhibition of NECA-induced cAMP accumulation measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50221683(9-(4-hydroxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)
Affinity DataKi:  630nMAssay Description:Displacement of [3H]MSX2 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50221683(9-(4-hydroxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)
Affinity DataKi:  7.20E+3nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50221683(9-(4-hydroxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PSB11 from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50221683(9-(4-hydroxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)
Affinity DataKi:  2.50E+4nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed