BDBM50221778 CHEMBL3216392

SMILES Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCCc1nc(O)c(CCCCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C

InChI Key InChIKey=PYLMQAOYRWPZPF-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221778   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institutes Of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50221778(CHEMBL3216392)
Affinity DataKi:  0.114nMAssay Description:Compound was tested for binding affinity towards Opioid receptor mu 1 by displacing [3H]DAGO radioligand in rat brain P2 synaptosomes membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institutes Of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50221778(CHEMBL3216392)
Affinity DataKi:  23nMAssay Description:Compound was tested for Opioid receptor mu 1 agonism in isolated tissues from guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Institutes Of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50221778(CHEMBL3216392)
Affinity DataIC50:  1.90nMAssay Description:Compound was tested for Opioid receptor mu 1 agonism in isolated tissues from guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
National Institutes Of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50221778(CHEMBL3216392)
Affinity DataIC50:  42nMAssay Description:pA2 is the negative log of the molar concentration required to double the agonism of opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed