BDBM50221944 1-(4-methyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)-4-(3-(trifluoromethyl)pyridin-2-yl)piperazine::CHEMBL247007

SMILES Cc1[nH]c(N2CCN(c3ncccc3C(F)(F)F)CC2)nc1-c1ccc(C(F)(F)F)cc1

InChI Key InChIKey=IUPFDVMGTMCZRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221944   

LigandChemical structure of BindingDB Monomer ID 50221944BDBM50221944(1-(4-methyl-5-(4-(trifluoromethyl)phenyl)-1H-imida...)
Affinity DataIC50: 628nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of capsaicin-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50221944BDBM50221944(1-(4-methyl-5-(4-(trifluoromethyl)phenyl)-1H-imida...)
Affinity DataIC50: 4.00E+3nMpH: 5.0Assay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of acid-induced calcium influx at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed