BDBM50221945 (4-isopropylpiperazin-1-yl)(5-(4-(trifluoromethyl)phenyl)-2-(4-(3-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-1H-imidazol-4-yl)methanone::CHEMBL393266

SMILES CC(C)N1CCN(C(=O)c2[nH]c(N3CCN(c4ncccc4C(F)(F)F)CC3)nc2-c2ccc(C(F)(F)F)cc2)CC1

InChI Key InChIKey=JSDJLJREZXCISB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221945   

LigandChemical structure of BindingDB Monomer ID 50221945BDBM50221945((4-isopropylpiperazin-1-yl)(5-(4-(trifluoromethyl)...)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of capsaicin-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50221945BDBM50221945((4-isopropylpiperazin-1-yl)(5-(4-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+3nMpH: 5.0Assay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of acid-induced calcium influx at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed