BDBM50221948 CHEMBL247858::N-(piperidin-2-ylmethyl)-5-(4-(trifluoromethyl)phenyl)-2-(4-(3-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-1H-imidazole-4-carboxamide

SMILES O=C(NCC1CCCCN1)c1[nH]c(N2CCN(c3ncccc3C(F)(F)F)CC2)nc1-c1ccc(C(F)(F)F)cc1

InChI Key InChIKey=PMASSUQNNSJZIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221948   

LigandChemical structure of BindingDB Monomer ID 50221948BDBM50221948(N-(piperidin-2-ylmethyl)-5-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 2.95E+3nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of capsaicin-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50221948BDBM50221948(N-(piperidin-2-ylmethyl)-5-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 4.00E+3nMpH: 5.0Assay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of acid-induced calcium influx at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed