BDBM50221952 (R)-(5-chloro-6-(3-methyl-4-(5-(4-(trifluoromethyl)phenyl)-4-(3,4,5-trifluorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)pyridin-3-yl)methanol::CHEMBL251094

SMILES C[C@@H]1CN(c2ncc(CO)cc2Cl)CCN1c1nc(-c2cc(F)c(F)c(F)c2)c(-c2ccc(C(F)(F)F)cc2)[nH]1

InChI Key InChIKey=XDNXJYNTLHMFAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221952   

LigandChemical structure of BindingDB Monomer ID 50221952BDBM50221952((R)-(5-chloro-6-(3-methyl-4-(5-(4-(trifluoromethyl...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of capsaicin-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50221952BDBM50221952((R)-(5-chloro-6-(3-methyl-4-(5-(4-(trifluoromethyl...)
Affinity DataIC50: 4nMpH: 5.0Assay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of acid-induced calcium influx at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed