BDBM50221958 1-(5-(4-(trifluoromethyl)phenyl)-4-(3,4,5-trifluorophenyl)-1H-imidazol-2-yl)-4-(3-(trifluoromethyl)pyridin-2-yl)piperazine::CHEMBL401332

SMILES Fc1cc(-c2nc(N3CCN(c4ncccc4C(F)(F)F)CC3)[nH]c2-c2ccc(C(F)(F)F)cc2)cc(F)c1F

InChI Key InChIKey=DMVKBKUYHCUYLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221958   

LigandChemical structure of BindingDB Monomer ID 50221958BDBM50221958(1-(5-(4-(trifluoromethyl)phenyl)-4-(3,4,5-trifluor...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of capsaicin-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50221958BDBM50221958(1-(5-(4-(trifluoromethyl)phenyl)-4-(3,4,5-trifluor...)
Affinity DataIC50: 20nMpH: 5.0Assay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of acid-induced calcium influx at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed