BDBM50222822 5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinic acid methyl ester::CHEMBL249028

SMILES COC(=O)c1cncc(NC(=O)COc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)c1

InChI Key InChIKey=OASPCDILGCFCDY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222822   

TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222822BDBM50222822(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222822BDBM50222822(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222822BDBM50222822(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed