BDBM50223023 5-(4,6-dimethylpyridin-2-yloxy)-N-((1R,2S)-2-ethoxy-2,3-dihydro-1H-inden-1-yl)-3,6-diethylpyrazin-2-amine::CHEMBL248785

SMILES CCO[C@H]1Cc2ccccc2[C@H]1Nc1nc(CC)c(Oc2cc(C)cc(C)n2)nc1CC

InChI Key InChIKey=OHGDKOGPXYYKAS-LADGPHEKSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223023   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50223023(5-(4,6-dimethylpyridin-2-yloxy)-N-((1R,2S)-2-ethox...)
Affinity DataKi:  22nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed