BDBM50223126 CHEMBL31715

SMILES CCCCc1nc(NCc2ccc(OC)cc2)c2sccc2n1

InChI Key InChIKey=LHTLSSNJQJFNAJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50223126   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50223126(CHEMBL31715)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against (PDE IV) phosphodiesterase IV in guinea pig articular tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50223126(CHEMBL31715)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223126(CHEMBL31715)
Affinity DataIC50:  1.70E+3nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223126(CHEMBL31715)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against cGMP inhibited Phosphodiesterase 3, isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed