BDBM50223145 CHEMBL398242::N-((R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-ylamino)-3-(2,6-dichlorophenyl)-1-oxopropan-2-yl)-4-fluoro-2-(trifluoromethyl)benzamide

SMILES CC(C)N1c2ccc(Cl)cc2CC[C@@H](NC(=O)[C@@H](Cc2c(Cl)cccc2Cl)NC(=O)c2ccc(F)cc2C(F)(F)F)C1=O

InChI Key InChIKey=INZHGKGGIQWGHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223145   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223145(N-((R)-1-((R)-7-chloro-1-isopropyl-2-oxo-2,3,4,5-t...)
Affinity DataIC50: 107nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed