BDBM50223150 CHEMBL250756::tert-butyl (R)-1-(9-isopropyl-8-oxo-6,7,8,9-tetrahydro-5H-pyrido[2,3-b]azepin-7-ylamino)-1-oxo-3-(2-(trifluoromethoxy)phenyl)propan-2-ylcarbamate

SMILES CC(C)N1c2ncccc2CCC(NC(=O)[C@@H](Cc2ccccc2OC(F)(F)F)NC(=O)OC(C)(C)C)C1=O

InChI Key InChIKey=BPUUWPHEQWHLAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223150   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223150(tert-butyl (R)-1-(9-isopropyl-8-oxo-6,7,8,9-tetrah...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human sodium channel Nav1.7 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed