BDBM50223617 CHEMBL95778

SMILES Cn1cc(\C=C\c2cc(nn2-c2cccc(Cl)c2)C2CCNCC2)c2cc(Cl)ccc12

InChI Key InChIKey=FNCACMZVIDUNBQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50223617   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223617(CHEMBL95778)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibitory activity against Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2018
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223617(CHEMBL95778)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibitory activity against supercoiling activity of DNA gyrase isolated from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223617(CHEMBL95778)
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibitory activity against decatenation of DNA topoisomerase IV isolated from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223617(CHEMBL95778)
Affinity DataIC50: 8.86E+5nMAssay Description:Human DNA topoisomerase II relaxation activity was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2018
Entry Details Article
PubMed