BDBM50223669 CHEMBL251603::N-(2-(4-methylpiperazin-1-yl)phenyl)-5-nitrofuran-2-carboxamide

SMILES CN1CCN(CC1)c1ccccc1NC(=O)c1ccc(o1)[N+]([O-])=O

InChI Key InChIKey=ICWQOMBLDBHQHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223669   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223669(N-(2-(4-methylpiperazin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 390nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223669(N-(2-(4-methylpiperazin-1-yl)phenyl)-5-nitrofuran-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed