BDBM50223672 CHEMBL250187::N-(2-((2Z,4Z,6Z)-1H-azepin-1-yl)phenyl)-5-nitrofuran-2-carboxamide

SMILES [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccccc1N1C=CC=CC=C1

InChI Key InChIKey=PJKUAPADAKZPKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223672   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223672(N-(2-((2Z,4Z,6Z)-1H-azepin-1-yl)phenyl)-5-nitrofur...)
Affinity DataIC50: 260nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223672(N-(2-((2Z,4Z,6Z)-1H-azepin-1-yl)phenyl)-5-nitrofur...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed