BDBM50224030 6-[4-(2-{[(2S)-2-hydroxy-3-{2'-oxo-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-4'-yloxy}propyl]amino}-2-methylpropyl)phenoxy]pyridine-3-carboxamide::CHEMBL248547

SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C3(CC3)c12

InChI Key InChIKey=WWQNLFHPDNSZMK-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224030   

TargetBeta-3 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50224030(6-[4-(2-{[(2S)-2-hydroxy-3-{2'-oxo-1',2'-dihydrosp...)
Affinity DataEC50:  6.60nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50224030(6-[4-(2-{[(2S)-2-hydroxy-3-{2'-oxo-1',2'-dihydrosp...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in CHO cells assessed as cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50224030(6-[4-(2-{[(2S)-2-hydroxy-3-{2'-oxo-1',2'-dihydrosp...)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed