BDBM50224208 2-(2-chlorophenylamino)-5-isopropylthiazol-4(5H)-one::CHEMBL235762

SMILES CC(C)c1sc(Nc2ccccc2Cl)nc1O

InChI Key InChIKey=CGWOWWGIXZJYDE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224208   

LigandPNGBDBM50224208(2-(2-chlorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224208(2-(2-chlorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224208(2-(2-chlorophenylamino)-5-isopropylthiazol-4(5H)-o...)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of human 11betaHSD2 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed