BDBM50224644 (4-(2-((S)-1-amino-2-methylpropyl)-6-fluorophenyl)piperazin-1-yl)((3S,4R)-4-(4-chlorophenyl)-1-cyclopentylpyrrolidin-3-yl)methanone::CHEMBL236527

SMILES CC(C)[C@H](N)c1cccc(F)c1N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1)C1CCCC1

InChI Key InChIKey=DYZKLCKHTWVRLI-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224644   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224644((4-(2-((S)-1-amino-2-methylpropyl)-6-fluorophenyl)...)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]NDP-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224644((4-(2-((S)-1-amino-2-methylpropyl)-6-fluorophenyl)...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as cAMP accumulation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed