BDBM50224646 (4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluoromethyl)phenyl)piperazin-1-yl)((3S,4R)-1-isopropyl-4-(4-methoxyphenyl)pyrrolidin-3-yl)methanone::CHEMBL235432

SMILES COc1ccc(cc1)[C@@H]1CN(C[C@H]1C(=O)N1CCN(CC1)c1ccc(cc1[C@@H](N)CC(C)C)C(F)(F)F)C(C)C

InChI Key InChIKey=SZEHNEVYJPISLX-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224646   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224646((4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluorometh...)
Affinity DataKi:  67nMAssay Description:Displacement of [125I]NDP-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50224646((4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluorometh...)
Affinity DataEC50:  450nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as cAMP accumulation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed