BDBM50225091 7-(3-(5-(3,5-dimethylphenyl)-4-(2-(4-(4-ethylhexyl)cyclohexyl)ethyl)-1,6-dihydropentalen-2-yl)-3-methylbut-1-en-2-yl)bicyclo[2.2.1]heptane::CHEMBL401081

SMILES CCN(CC)CCOC1CCN(CCc2c([nH]c3sc(cc23)C(C)(C)C(=O)N2C3CCC2CC3)-c2cc(C)cc(C)c2)CC1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50225091   

TargetGonadotropin-releasing hormone receptor(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225091(7-(3-(5-(3,5-dimethylphenyl)-4-(2-(4-(4-ethylhexyl...)
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225091(7-(3-(5-(3,5-dimethylphenyl)-4-(2-(4-(4-ethylhexyl...)
Affinity DataIC50: 33nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225091(7-(3-(5-(3,5-dimethylphenyl)-4-(2-(4-(4-ethylhexyl...)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pituitary cells assessed as inhibition of GnRH stimulated LH release afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed