BDBM50225092 (S)-N-(2-(2-(1-(7-aza-bicyclo[2.2.1]heptan-7-yl)-2-methyl-1-oxopropan-2-yl)-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrol-4-yl)propyl)-4-(pyridin-4-yl)piperidine-1-carboxamide::CHEMBL399779

SMILES C[C@H](CNC(=O)N1CCC(CC1)c1ccncc1)c1c([nH]c2sc(cc12)C(C)(C)C(=O)N1C2CCC1CC2)-c1cc(C)cc(C)c1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50225092   

TargetGonadotropin-releasing hormone receptor(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225092((S)-N-(2-(2-(1-(7-aza-bicyclo[2.2.1]heptan-7-yl)-2...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225092((S)-N-(2-(2-(1-(7-aza-bicyclo[2.2.1]heptan-7-yl)-2...)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pituitary cells assessed as inhibition of GnRH stimulated LH release afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225092((S)-N-(2-(2-(1-(7-aza-bicyclo[2.2.1]heptan-7-yl)-2...)
Affinity DataIC50: 56nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed